Toregem Biopharma Company Is Developing A Drug for Dental Restoration
Toregem Biopharma, a Japanese biotech company, is on the verge of a breakthrough in dentistry by developing an antibody-based drug that can stimulate the growth of new teeth. This innovative drug is designed to suppress the action of a protein that stops the development of teeth. Previously, it had already been successfully tested on mice, which as a result had new teeth in place of the lost ones.
Toregem Biopharma aims to bring the drug to market by 2030. Initially, it is planned that it will be intended for people suffering from congenital anodontia, a condition in which partial or complete absence of teeth occurs from birth. However, the company plans to subsequently offer a remedy for people who lost their teeth later, for various reasons.
Anodontia
Anodontia is a rare disease that occurs in about 0.1% of the population. People with this disease usually have to install dental implants or dentures, as there is currently no treatment that can eliminate the root cause of the disease. The drug from Toregem Biopharma may become the first in the world that solves the problem of anodontia at the root level, stimulating the growth of teeth.
The co-founder of the company, Katsus Takahashi, said that the first phase of clinical trials will focus on verifying the safety of the drug. For this purpose, 30 healthy adult men will be involved. These tests will begin in 2024.
Release Dates Of The Drug
The next stage of clinical trials is planned for 2025, and it will be aimed at studying the effectiveness of the drug in the treatment of children with congenital anodontia aged two to seven years. If the trials are successful, Toregem Biopharma will take a step towards a revolution in dentistry by offering a new way to restore lost teeth.
This discovery has a potentially huge social and medical effect. If everything goes according to plan, by 2030, a product will appear on the market that can significantly improve the quality of life of people suffering from anodontia or tooth loss.